The long term research objective of the Shen-Orr Systems Immunology Lab is to understand how immunity is orchestrated in man and to apply this knowledge towards advancing genomic medicine.
To achieve this goal, we combine experimental and computational approaches to cover three main themes, spanning between clinical and basic research: First, we aim to identify biomarkers monitoring health and immune health in particular.Second, we aim to study how to efficiently translate our understanding of biology from model organisms to humans and third, we aim to understand the system level properties of immunity and harness these insights to understand complex systems in general.